Simultaneous epicardial and endocardial activation sequence mapping in the isolated canine right atrium.
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چکیده
منابع مشابه
Simultaneous epicardial and endocardial activation sequence mapping in the isolated canine right atrium.
BACKGROUND Since the atria are thin-walled structures, most studies that have examined the spread of activation in the atria have assumed that they behave electrophysiologically as a two-dimensional surface. It was the objective of this study to determine whether or not this assumption is true by simultaneously mapping the epicardial and endocardial activation sequences in the right atrium. M...
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Epicardial high-density electrical mapping is a well-established experimental instrument to monitor in vivo the activity of the atria in response to modulations of the autonomic nervous system in sinus rhythm. In regions that are not accessible by epicardial mapping, noncontact endocardial mapping performed through a balloon catheter may provide a more comprehensive description of atrial activi...
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The mechanisms of sinoatrial node (SAN) dysfunction in patients with chronically elevated sympathetic tone and reduced pacemaker current (I(f); such as heart failure) are poorly understood. We simultaneously mapped membrane potential and intracellular Ca(2+) in the Langendorff-perfused canine right atrium (RA). Blockade of either I(f) (ZD-7288) or sarcoplasmic reticulum Ca(2+) release (ryanodin...
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ژورنال
عنوان ژورنال: Circulation
سال: 1993
ISSN: 0009-7322,1524-4539
DOI: 10.1161/01.cir.88.1.250